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The Steering Committee
Alastair Carruthers, MD, FRCP(C)
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In the News

This section informs healthcare professionals of the latest medical information via daily news articles on aesthetic enhancement and other related areas.

Recent Headlines
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Risky Skin-Care Habits Increasing Among Asian-Americans
May 19, 2009 -- A new survey from the Stanford University School of Medicine suggests that a significant number of Asian Americans living in California adopt unhealthy sun-exposure behaviors as they become more westernized. The findings underscore a need for increased skin-health awareness on the part of primary care physicians, dermatologists and people of Asian ancestry, who may incorrectly assume that pigmented skin and hair protect against skin cancer.

Risk Of Facial Fractures In Motor Vehicle Crashes Decreasing
May 19, 2009 -- Facial fractures from motor vehicle crashes appear to be decreasing, most likely due to design improvements in newer vehicles, according to a report in the May/June issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals. Facial trauma is the most common injury among individuals involved in motor vehicle collisions, according to background information in the article.

Pelleve Receives FDA Clearance For The Treatment Of Mild To Moderate Facial Wrinkles
May 19, 2009 -- Ellman International, Inc. announced that the Food and Drug Administration (FDA) has granted clearance to Pelleve(TM), a skin tightening system for the non-ablative treatment of mild to moderate facial wrinkles and rhytids for skin phototypes I-IV. The clearance was granted based on clinical data demonstrating that a single treatment with the high frequency radiowave device can safely and effectively tighten and improve the appearance of skin on the face through six months.

Provectus Completes Patient Accrual In Phase 2 Trial Of PV-10 For Metastatic Melanoma
May 19, 2009 -- Provectus Pharmaceuticals, Inc. (OTC BB: PVCT), a development-stage oncology and dermatology biopharmaceutical company has completed patient accrual and initial PV-10 treatment in its Phase 2 trial of PV-10 for metastatic melanoma. The study involved treatment of 80 subjects with Stage III or Stage IV metastatic melanoma. Dr.

Get Screened: Early Detection Is The Key To Successful Skin Cancer Treatment
May 18, 2009 -- The bad news: Skin cancer is the most common of all cancers, accounting for 40% of all carcinoma diagnoses. More than 1.6 million new cases of skin cancer were diagnosed last year, resulting in the death of more than 11,000 people. The good news: Most skin cancers-even melanoma, the most serious form-can be treated successfully if detected early. To this end, the American Cancer Society recommends a skin examination as part of periodic checkups for people age 20 and older.

Triple Drug Combination Is Promising Option To Treat Metastatic HER2+ Breast Cancer
May 18, 2009 -- Combining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options.

Dynavax Awarded Grant To Support Development Of TLR Inhibitors In Skin Diseases
May 15, 2009 -- Dynavax Technologies Corporation (Nasdaq:DVAX) announced the award of a Small Business Innovation Research (SBIR) grant by the National Institute of Allergy and Infectious Diseases (NIAID). This grant will support the preclinical development of Dynavax's first-in-class oligonucleotide-based Toll-like Receptor (TLR) inhibitors for use in inflammatory skin diseases such as psoriasis, cutaneous lupus, and dermatomyositis. This new two-year $700,000 grant is in addition to a $1.

ZymoGenetics Reports Encouraging Preliminary Results From Phase 2 Study Of IL-21 In Metastatic Melanoma Conducted By NCIC
May 15, 2009 -- ZymoGenetics, Inc. (NASDAQ:ZGEN) announced that Interleukin 21 (IL-21) demonstrated an impressive overall response rate in the treatment of metastatic melanoma. In interim Phase 2 results from 24 patients, 29 percent showed a partial response, with an additional 33 percent of patients showing stable disease in this difficult to treat disease. "We are seeing promising anti-tumor response with IL-21 in patients with metastatic melanoma in this Phase 2 study," said Nicole Onetto, M.D.

New EU Regulations Force Cosmetics Firms To Abandon Safety Tests In Animals
May 14, 2009 -- New European Union (EU) regulations restricting use of animals to test the safety of shampoo, nail polish, and other personal care products are forcing cosmetic makers to seek alternative ways to test these products, according to an article scheduled for the May 11 issue of Chemical & Engineering News, ACS' weekly newsmagazine.

Molecular Structure Could Help Explain Albinism, Melanoma
May 13, 2009 -- Arthropods and mollusks are Nature's true bluebloods - thanks to hemocyanin, an oxygen-carrying large protein complex, which can even be turned into the enzymatically active chemical phenoloxidase. Scientists have long known that members of the phenoloxidase family are involved in skin and hair coloring. When they are mutated, they can cause albinism - the loss of coloring in skin and hair. Produced over abundantly, they are associated with the deadly skin cancer melanoma.

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